Classifying Lupus Nephritis: An Ongoing Story

Classifying Lupus Nephritis: An Ongoing Story

The role of the renal biopsy in lupus nephritis is to provide the diagnosis and to define the parameters of prognostic and therapeutic significance for an effective clinicopathological correlation. Various classification schemas initiated by World Health Organization in 1974 have been proposed until the most recent update by International Society of Nephrology/Renal Pathology Society in 2004. I...

Lupus nephritis in Bangladesh: unfolding the story

L upus nephritis (LN) represents the most dreadful complication of patients with systemic lupus erythematosus (SLE). It is responsible for a major share of morbidity and mortality in these patients. The rate of development of this complication varies widely (1,2). The reported figures vary from 40% to 80%. LN can involve any of the four components of the kidney parenchyma in variable combinatio...

TiO2 nanoparticle toxicity – an ongoing story

Twin registries: an ongoing success story.

grant application for a twin heritability and linkage study on the grounds that ‘twin studies were an outdated methodology with no scientific merit, publishable only in obscure journals if anything ...’. Neither Twin Research and Human Genetics nor any of the other peer-reviewed journals cited by the authors of this special issue warrants the term ‘obscure’. Rather than being ‘outdated’, twin r...

The metabolic syndrome - an ongoing story.

The metabolic syndrome refers to the clustering of cardiovascular risk factors that include diabetes, obesity, dyslipidaemia and hypertension. Due to various definitions and unexplained pathophysiology it is still a source of medical controversy. Insulin resistance and visceral obesity have been recognized as the most important pathogenic factors. Insulin resistance could be defined as the inab...